Head-to-head comparative trials for first line ART since 2006

Comparison of NRTI combinations

ZDV/3TC vs TDF + FTC
934
ABC/3TC vs TDF/FTC
HEAT
A5202
ASSERT
FTC/TDF vs FTC/TAF
Studies GS-US-292-0104 and GS-US-292-0111
AMBER

Comparison of NNRTI vs NNRTI

ENCORE
EFV vs RPV
ECHO-THRIVE
STAR
EFV vs ETR
SENSE
EFV vs DOR
DRIVE-AHEAD

Comparison of NNRTI vs PI/r

EFV vs LPV/r vs EFV + LPV/r
A5142
Mexican Study
NVP vs ATV/r
ARTEN
EFV vs ATV/r
A5202
DOR vs DRV/r
DRIVE-FORWARD

Comparison of PI vs PI

ATV vs ATV/r
BMS 089
LPV/r mono vs LPV/r + ZDV/3TC
MONARK
LPV/r QD vs BID
M02-418
M05-730
A5073
LPV/r + 3TC vs LPV/r + 2 NRTI
GARDEL
ATV/r vs FPV/r
ALERT
ATV/r vs DRV/r
ATADAR
FPV/r vs LPV/r
KLEAN
SQV/r vs LPV/r
GEMINI
ATV/r vs LPV/r
CASTLE
DRV/r vs LPV/r
ARTEMIS
DRV/r + 3TC vs DRV/r + 3TC/TDF
ANDES

Comparison of RTV vs Cobi

GS-US-216-0114

Comparison of INSTI vs INSTI

QDMRK
SPRING-2
ONCEMRK
GS-US_380-1489
GS-US_380-1490

Comparison of INSTI vs EFV

STARTMRK
GS-US-236-0102
SINGLE

Comparison of INSTI vs PI

FLAMINGO
GS-236-0103
ACTG A5257
WAVES
ARIA

Comparison of EFV vs MVC

MERIT

NRTI-Sparing

SPARTAN
PROGRESS
RADAR
NEAT 001/ANRS 143
A4001078
VEMAN
MODERN

Intensification with INSTI

REALITY

Anton Pozniak

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